ASCLS eNewsBytes

• Aspergillus Osteomyelitis Remains Rare but Treatable January 12, 2026
  A retrospective analysis from two major U.S. academic centers sheds light on the clinical features, management strategies and outcomes associated with Aspergillus osteomyelitis, which is a rare form of invasive aspergillosis.
• Combining Pembrolizumab With Low-Dose Radiation in Early Triple-Negative Breast Cancer January 12, 2026
  Advancements in cancer treatment focus on combining various approaches to enhance patient outcomes and reduce side effects, integrating drugs with distinct mechanisms and pairing systemic therapies like chemotherapy or immunotherapy with local treatments such as surgery or radiation.
• FDA Approves Novel Fibrinogen Concentrate for CFD January 12, 2026
  The FDA has approved fibrinogen, human-chmt, a new fibrinogen concentrate, for treating acute bleeding episodes in pediatric and adult patients with congenital fibrinogen deficiency. It is specifically indicated for acute bleeding related to hypo- or afibrinogenemia but not for dysfibrinogenemia.
• Researchers Identify Proteins that Spread Parkinson's Pathology in the Brain January 12, 2026
  Two proteins on motor neurons' surfaces may play a crucial role in Parkinson's disease progression, a neurodegenerative disorder characterized by the gradual degeneration and death of brain neurons due to the buildup of a misfolded protein known as α-synuclein, which propagates between neurons.
• Blood Tests Reveal How Quickly Obesity Accelerates Alzheimer's January 12, 2026
  Researchers' study reveals that obesity significantly accelerates the increase of blood biomarkers associated with Alzheimer's disease, with levels rising up to 95% faster in individuals with obesity compared to those without.