ASCLS eNewsBytes

• Researchers identify genetic factors associated with drug resistance in prostate cancer September 26, 2022
  In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. "We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]
• Genetic tests create treatment opportunities and confusion for breast cancer patients September 26, 2022
  The past decade has witnessed a rapid expansion of genetic tests, including new instruments to inform patients who have been diagnosed with breast cancer about the risk of recurrence and to guide their treatment. However, the clinical significance of many of the inherited mutations that can now be identified remains unclear, and experts are torn […]
• Monkeypox outbreaks associated with human-to-human transmission outside endemic areas September 26, 2022
  Since May 2022, cases of monkeypox have increased globally, stirring fears of a new pandemic. A study published in the open-access journal PLOS Pathogens on September 22 by Professor Souha Kanj and colleagues at the American University of Beirut Medical Center, Beirut, Lebanon, presents synthesized descriptions of its clinical characteristics, risk factors, infection control and […]
• Computer simulations visualize how an essential stem cell protein opens wrapped DNA September 26, 2022
  A key protein for converting adult stem cells into cells that resemble embryonic stem cells has been visualized in unprecedented detail by an international team of researchers around Hans Schöler and Vlad Cojocaru of the Max Planck Institute for Molecular Biomedicine in Münster. By combining experiments and computer simulations, the team visualized how the Oct4 […]
• Using HyperExome probes for DNA hybridization workflows September 26, 2022
  Each year, the uptake and utilization of automation in the clinical laboratory is increasing at a rate of over 30%. This is rapidly advancing the development of new technologies and driving the early adoption of new next-generation sequencing applications in the laboratory. The demand for clinical NGS is anticipated to grow by around 350% over […]