ASCLS eNewsBytes

• Construction of a Nomogram Model Based On Multiple Factors To Differentiate Cryptococcal Meningitis From Tuberculous Meningitis in HIV-Infected Patients April 15, 2025
  A nomogram model was developed to differentiate cryptococcal meningitis from tuberculous meningitis in HIV-infected patients, using key predictor variables and LASSO regression analysis.
• Adult Intussusception Secondary to Varicella-Zoster Virus Infection April 15, 2025
  This case explores the unusual presentation of intussusception in varicella infection, emphasizing the importance of early diagnosis and targeted management, and the need for further investigation.
• Next-Generation COVID-19 Vaccines Currently Being Tested April 15, 2025
  Three companies, INOVIO, Ocugen and Pfizer, have announced advancements in clinical research for next-generation Covid-19 vaccines, ensuring continued development and adaptation to evolving virus cases.
• Selective CDK4 Inhibition Holds Promise for Breast Cancer April 15, 2025
  U.S. FDA approves palbociclib, ribociclib and abemaciclib for use with hormonotherapy in advanced HR+HER2− breast cancer patients, showing overall survival advantage, but hematological side effects.
• The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells April 15, 2025
  A system efficiently guides human embryonic stem cells into nociceptive neurons by inducing them to the neural lineage, then adding retinoic acid and BMP4 at specific concentrations.