ASCLS eNewsBytes

• FDA Approves First Drug for Pediatrics With Irritable Bowel Syndrome With Constipation November 11, 2025
  The FDA has approved linaclotide capsules for pediatric patients aged seven and older with irritable bowel syndrome with constipation, marking the first treatment for IBS-C in this age group.
• Scientists Map 17,000 Gene Variants Linked to Early Heart Disease November 11, 2025
  An international research consortium has mapped over 17,000 variants in a gene linked to premature atherosclerotic heart disease. This study aims to enhance early diagnosis and treatment of familial hypercholesterolemia, a prevalent genetic cause of cardiovascular disease affecting approximately 1 in 250 individuals.
• FDA Approves IV Antibiotic, Contepo, for Complicated Urinary Tract Infections November 11, 2025
  The U.S. FDA has approved fosfomycin for treating complicated urinary tract infections in adults caused by susceptible strains of Escherichia coli and Klebsiella pneumoniae.
• COVID-19 Vaccination Linked to Reduced Infections in Children with Eczema November 11, 2025
  Children with atopic dermatitis may have a reduced risk of infections and allergic complications if vaccinated against COVID-19. Atopic dermatitis is a chronic skin condition linked to immune system responses and is often a precursor to asthma and allergic rhinitis.
• Scientists Discover How Hair Cells Can Help Heal Skin Faster November 11, 2025
  Scientists found that hair follicle stem cells can shift from hair growth to skin repair when nutrient levels, particularly serine, drop. Serine activates a stress signal for energy conservation, directing stem cells to prioritize skin repair during injury and low nutrient availability.