ASCLS eNewsBytes

• NIH trial of rectal microbicide for HIV prevention begins in the US November 5, 2024
  The National Institutes of Health is conducting a clinical trial to evaluate the safety and acceptability of a rectal HIV microbicide douche containing tenofovir, an antiretroviral drug. The "on-demand" HIV prevention approach aims to expand the options for eligible individuals engaging in receptive anal intercourse.
• Antibody-based treatment for the most aggressive type of breast cancer could also treat other cancers November 5, 2024
  Researchers at the Weizmann Institute of Science have discovered that aggressive breast cancer prompts immune cells to build "molecular bridges" between themselves, leading to immune suppression. The researchers identified CD84, a protein4, that is used to construct these bridges, and developed an antibody that blocks these bridges, slowing down the disease.
• US FDA approves Journey Medical's drug for long-term skin condition November 5, 2024
  Journey Medical has been approved by the FDA for its oral antibiotic, Emrosi, to treat rosacea, a long-term skin condition causing chronic inflammation. The FDA concerns the prevalence of erythema across other types of rosacea, which could lead to confusion among providers.
• Increase in blood-fat disorder risk linked to COVID-19 pandemic November 5, 2024
  A study by Albert Einstein College of Medicine found that the COVID-19 pandemic increased the risk of developing dyslipidemia, a condition involving abnormal lipid levels in the blood. Seniors and people with Type 2 diabetes were more affected, experiencing a two-fold increase in dyslipidemia risk.
• FDA approves botox cosmetic for moderate-to-severe neck bands November 5, 2024
  Allergan Aesthetics has received FDA approval for Botox Cosmetic, a nonsurgical, injectable treatment for moderate-to-severe vertical bands connecting the jaw and neck in adults. The product works beneath the surface to temporarily reduce underlying muscle activity, improving the appearance of the bands connecting the neck and jaw.